Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice

Abnormalities in hepatic lipid metabolism and insulin action are believed to play a critical role in the etiology of nonalcoholic steatohepatitis. Monoacylglycerol acyltransferase (MGAT) enzymes convert monoacylglycerol to diacylglycerol, which is the penultimate step in one pathway for triacylglyce...

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Main Authors: Soufi, Nisreen, Hall, Angela M., Chen, Zhouji, Yoshino, Jun, Collier, Sara L., Mathews, James C., Brunt, Elizabeth M., Albert, Carolyn J., Graham, Mark J., Ford, David A., Finck, Brian N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208022/
https://ncbi.nlm.nih.gov/pubmed/25213859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595850
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