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Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9

The serine hydrolases constitute a large class of enzymes that play important roles in physiology. There is great interest in the development of potent and selective pharmacological inhibitors to these proteins. Traditional active site inhibitors often have limited selectivity within this superfamil...

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Bibliografski detalji
Glavni autori: Liu, Xiaodan, Dix, Melissa, Speers, Anna E., Bachovchin, Daniel A., Zuhl, Andrea M., Cravatt, Benjamin F., Kodadek, Thomas
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777423/
https://ncbi.nlm.nih.gov/pubmed/22907802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200445
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