RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia

Pancreatic cancer is one of the most lethal malignancies. To discover functionally relevant modulators of pancreatic neoplasia, we performed activity-based proteomic profiling on primary human ductal adenocarcinomas. Here, we identify retinoblastoma-binding protein 9 (RBBP9) as a tumor-associated se...

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Détails bibliographiques
Auteurs principaux: Shields, David J., Niessen, Sherry, Murphy, Eric A., Mielgo, Ainhoa, Desgrosellier, Jay S., Lau, Steven K. M., Barnes, Leo A., Lesperance, Jacqueline, Bouvet, Michael, Tarin, David, Cravatt, Benjamin F., Cheresh, David A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836678/
https://ncbi.nlm.nih.gov/pubmed/20080647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911646107
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