RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia

Pancreatic cancer is one of the most lethal malignancies. To discover functionally relevant modulators of pancreatic neoplasia, we performed activity-based proteomic profiling on primary human ductal adenocarcinomas. Here, we identify retinoblastoma-binding protein 9 (RBBP9) as a tumor-associated se...

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Autori principali: Shields, David J., Niessen, Sherry, Murphy, Eric A., Mielgo, Ainhoa, Desgrosellier, Jay S., Lau, Steven K. M., Barnes, Leo A., Lesperance, Jacqueline, Bouvet, Michael, Tarin, David, Cravatt, Benjamin F., Cheresh, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836678/
https://ncbi.nlm.nih.gov/pubmed/20080647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911646107
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