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Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression
Integrins regulate adhesion-dependent growth, survival and invasion of tumor cells. In particular, expression of integrin αvβ3 is associated with progression of a variety of human tumors. Here, we reveal a novel adhesion-independent role for integrin αvβ3 in pancreatic cancer and other carcinomas. S...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759406/ https://ncbi.nlm.nih.gov/pubmed/19734908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2009 |
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