Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression

Integrins regulate adhesion-dependent growth, survival and invasion of tumor cells. In particular, expression of integrin αvβ3 is associated with progression of a variety of human tumors. Here, we reveal a novel adhesion-independent role for integrin αvβ3 in pancreatic cancer and other carcinomas. S...

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Detaylı Bibliyografya
Asıl Yazarlar: Desgrosellier, Jay S, Barnes, Leo A, Shields, David J, Huang, Miller, Lau, Steven K, Prévost, Nicolas, Tarin, David, Shattil, Sanford J, Cheresh, David A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759406/
https://ncbi.nlm.nih.gov/pubmed/19734908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2009
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