A precision approach to breast cancer treatment based on cell lineage-specific vulnerabilities

le Desgrosellier, Jay S.
Foilsithe in Oncoscience (2021)

Integrins in cancer: biological implications and therapeutic opportunities

le Desgrosellier, Jay S., Cheresh, David A.
Foilsithe in Nat Rev Cancer (2010)

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

le Seguin, Laetitia, Desgrosellier, Jay S., Weis, Sara M., Cheresh, David A.
Foilsithe in Trends Cell Biol (2015)

4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cel...

le Russo, James, Barnes, Annette, Berger, Katie, Desgrosellier, Jay, Henderson, Jennifer, Kanters, Ana, Merkov, Lubo
Foilsithe 2002

Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis

le Sun, Qi, Lesperance, Jacqueline, Wettersten, Hiromi, Luterstein, Elaine, DeRose, Yoko S., Welm, Alana, Cheresh, David A., Desgrosellier, Jay S.
Foilsithe in J Clin Invest (2017)

Integrin αvβ3 Drives Slug Activation and Stemness in the Pregnant and Neoplastic Mammary Gland

le Desgrosellier, Jay S, Lesperance, Jacqueline, Seguin, Laetitia, Gozo, Maricel, Kato, Shumei, Franovic, Aleksandra, Yebra, Mayra, Shattil, Sanford J, Cheresh, David A
Foilsithe 2014

EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation

le Huang, Miller, Anand, Sudarshan, Murphy, Eric A., Desgrosellier, Jay S., Stupack, Dwayne G., Shattil, Sanford J., Schlaepfer, David D., Cheresh, David A.
Foilsithe 2011

Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression

le Desgrosellier, Jay S, Barnes, Leo A, Shields, David J, Huang, Miller, Lau, Steven K, Prévost, Nicolas, Tarin, David, Shattil, Sanford J, Cheresh, David A
Foilsithe 2009

Galectin-3, a druggable vulnerability for KRAS-addicted cancers

le Seguin, Laetitia, Camargo, Maria F., Wettersten, Hiromi I., Kato, Shumei, Desgrosellier, Jay S., von Schalscha, Tami, Elliott, Kathryn C., Cosset, Erika, Lesperance, Jacqueline, Weis, Sara M., Cheresh, David A.
Foilsithe in Cancer Discov (2017)

RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia

le Shields, David J., Niessen, Sherry, Murphy, Eric A., Mielgo, Ainhoa, Desgrosellier, Jay S., Lau, Steven K. M., Barnes, Leo A., Lesperance, Jacqueline, Bouvet, Michael, Tarin, David, Cravatt, Benjamin F., Cheresh, David A.
Foilsithe 2009

EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin αvβ5 Depends on Activation of c-Src and Cleavage of MUC1

le Lau, Steven K. M., Shields, David J., Murphy, Eric A., Desgrosellier, Jay S., Anand, Sudarshan, Huang, Miller, Kato, Shumei, Lim, Ssang-Taek, Weis, Sara M., Stupack, Dwayne G., Schlaepfer, David D., Cheresh, David A.
Foilsithe 2012

PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes

le Garmy-Susini, Barbara, Avraamides, Christie J., Desgrosellier, Jay S., Schmid, Michael C., Foubert, Philippe, Ellies, Lesley G., Lowy, Andrew M., Blair, Sarah L., Vandenberg, Scott R., Datnow, Brian, Wang, Huan-You, Cheresh, David A., Varner, Judith
Foilsithe 2013

A β3 integrin-KRAS-RalB complex drives tumor stemness and resistance to EGFR inhibition

le Seguin, Laetitia, Kato, Shumei, Franovic, Aleksandra, Camargo, M. Fernanda, Lesperance, Jacqueline, Elliott, Kathryn C., Yebra, Mayra, Mielgo, Ainhoa, Lowy, Andrew M., Husain, Hatim, Cascone, Tina, Diao, Lixia, Wang, Jing, Wistuba, Ignacio I., Heymach, John V., Lippman, Scott M., Desgrosellier, Jay S., Anand, Sudarshan, Weis, Sara M., Cheresh, David A.
Foilsithe 2014