Targeting the Achilles’ heel of drug-resistant cancer stem cells

Por Seguin, Laetitia, Gozo, Maricel, Weis, Sara M, Cheresh, David A
Publicado em 2014

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

Por Seguin, Laetitia, Desgrosellier, Jay S., Weis, Sara M., Cheresh, David A.
Publicado no Trends Cell Biol (2015)

APC(cdh1) Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis

Por Liot, Caroline, Seguin, Laetitia, Siret, Aurélie, Crouin, Catherine, Schmidt, Susanne, Bertoglio, Jacques
Publicado em 2011

CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase

Por Seguin, Laetitia, Liot, Caroline, Mzali, Rym, Harada, Ryoko, Siret, Aurelie, Nepveu, Alain, Bertoglio, Jacques
Publicado em 2009

Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence

Por Franovic, Aleksandra, Elliott, Kathryn C., Seguin, Laetitia, Camargo, M. Fernanda, Weis, Sara M., Cheresh, David A.
Publicado no Cancer Res (2015)

Integrin αvβ3 Drives Slug Activation and Stemness in the Pregnant and Neoplastic Mammary Gland

Por Desgrosellier, Jay S, Lesperance, Jacqueline, Seguin, Laetitia, Gozo, Maricel, Kato, Shumei, Franovic, Aleksandra, Yebra, Mayra, Shattil, Sanford J, Cheresh, David A
Publicado em 2014

A MEK-independent role for CRAF in mitosis and tumor progression

Por Mielgo, Ainhoa, Seguin, Laetitia, Huang, Miller, Camargo, Maria Fernanda, Anand, Sudarshan, Franovic, Aleksandra, Weis, Sara M., Advani, Sunil J., Murphy, Eric A., Cheresh, David A.
Publicado em 2011

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2

Por Advani, Sunil J., Camargo, Maria Fernanda, Seguin, Laetitia, Mielgo, Ainhoa, Anand, Sudarshan, Hicks, Angel M., Aguilera, Joseph, Franovic, Aleksandra, Weis, Sara M., Cheresh, David A.
Publicado no Nat Commun (2015)

Galectin-3, a druggable vulnerability for KRAS-addicted cancers

Por Seguin, Laetitia, Camargo, Maria F., Wettersten, Hiromi I., Kato, Shumei, Desgrosellier, Jay S., von Schalscha, Tami, Elliott, Kathryn C., Cosset, Erika, Lesperance, Jacqueline, Weis, Sara M., Cheresh, David A.
Publicado no Cancer Discov (2017)

A β3 integrin-KRAS-RalB complex drives tumor stemness and resistance to EGFR inhibition

Por Seguin, Laetitia, Kato, Shumei, Franovic, Aleksandra, Camargo, M. Fernanda, Lesperance, Jacqueline, Elliott, Kathryn C., Yebra, Mayra, Mielgo, Ainhoa, Lowy, Andrew M., Husain, Hatim, Cascone, Tina, Diao, Lixia, Wang, Jing, Wistuba, Ignacio I., Heymach, John V., Lippman, Scott M., Desgrosellier, Jay S., Anand, Sudarshan, Weis, Sara M., Cheresh, David A.
Publicado em 2014

Glut3 addiction is a druggable vulnerability for a molecularly defined subpopulation of glioblastoma

Por Cosset, Érika, Ilmjärv, Sten, Dutoit, Valérie, Elliott, Kathryn, von Schalscha, Tami, Camargo, Maria F., Reiss, Alexander, Moroishi, Toshiro, Seguin, Laetitia, Gomez, German, Moo, Jung-Soon, Preynat-Seauve, Olivier, Krause, Karl-Heinz, Chneiweiss, Hervé, Sarkaria, Jann N., Guan, Kun-Liang, Dietrich, Pierre-Yves, Weis, Sara M., Mischel, Paul S., Cheresh, David A.
Publicado no Cancer Cell (2017)