EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation

Tyrosine kinase receptors play an essential role in various aspects of tumor progression. In particular, epidermal growth factor receptor (EGFR) and its ligands have been implicated in the growth and dissemination of a wide array of human carcinomas. Here, we describe an EGFR-mediated signaling path...

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Detalhes bibliográficos
Main Authors: Huang, Miller, Anand, Sudarshan, Murphy, Eric A., Desgrosellier, Jay S., Stupack, Dwayne G., Shattil, Sanford J., Schlaepfer, David D., Cheresh, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711644/
https://ncbi.nlm.nih.gov/pubmed/21963850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.450
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