Applications of Metabolomics for Kidney Disease Research: From biomarkers to therapeutic targets

Por Wettersten, Hiromi I., Weiss, Robert H.
Publicado em 2013

Inhibition of PPARα Induces Cell Cycle Arrest and Apoptosis, and Synergizes with Glycolysis Inhibition in Kidney Cancer Cells

Por Abu Aboud, Omran, Wettersten, Hiromi I., Weiss, Robert H.
Publicado em 2013

Small-molecule inhibitors of p21 as novel therapeutics for chemotherapy-resistant kidney cancer

Por Liu, Ruiwu, Wettersten, Hiromi I., Park, See-Hyoung, Weiss, Robert H.
Publicado no Future Med Chem (2013)

Specific Inhibition of the Nuclear Exporter Exportin-1 Attenuates Kidney Cancer Growth

Por Wettersten, Hiromi I., Landesman, Yosef, Friedlander, Sharon, Shacham, Sharon, Kauffman, Michael, Weiss, Robert H.
Publicado no PLoS One (2014)

From bead to flask: Synthesis of a complex β-amido-amide for probe-development studies

Por Martin, Kevin S, Soldi, Cristian, Candee, Kellan N, Wettersten, Hiromi I, Weiss, Robert H, Shaw, Jared T
Publicado em 2013

A novel p21 attenuator which is structurally related to sorafenib

Por Wettersten, Hiromi I., Hee Hwang, Sung, Li, Cuiwen, Shiu, Eunice Y., Wecksler, Aaron T., Hammock, Bruce D., Weiss, Robert H.
Publicado em 2013

Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK4 levels

Por Tan, Matthew, Wettersten, Hiromi I., Chu, Kristy, Huso, David L., Watnick, Terry, Friedlander, Sharon, Landesman, Yosef, Weiss, Robert H.
Publicado no Am J Physiol Renal Physiol (2014)

Biological evaluation of a novel sorafenib analogue, t-CUPM

Por Wecksler, Aaron T., Hwang, Sung Hee, Liu, Jun-Yan, Wettersten, Hiromi I., Morisseau, Christophe, Wu, Jian, Weiss, Robert H., Hammock, Bruce D.
Publicado no Cancer Chemother Pharmacol (2014)

Mealtime, Temporal, and Daily Variability of the Human Urinary and Plasma Metabolomes in a Tightly Controlled Environment

Por Kim, Kyoungmi, Mall, Christine, Taylor, Sandra L., Hitchcock, Stacie, Zhang, Chen, Wettersten, Hiromi I., Jones, A. Daniel, Chapman, Arlene, Weiss, Robert H.
Publicado em 2014

Novel Sorafenib-Based Structural Analogues: In Vitro Anticancer Evaluation of t-MTUCB and t-AUCMB

Por Wecksler, Aaron T., Hwang, Sung Hee, Wettersten, Hiromi I., Gilda, Jennifer E., Patton, Amy, Leon, Leonardo J., Carraway, Kermit L., Gomes, Aldrin V., Baar, Keith, Weiss, Robert H., Hammock, Bruce D.
Publicado em 2014

Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer

Por Trott, Josephine F., Kim, Jeffrey, Aboud, Omran Abu, Wettersten, Hiromi, Stewart, Benjamin, Berryhill, Grace, Uzal, Francisco, Hovey, Russell C., Chen, Ching-Hsien, Anderson, Katie, Graef, Ashley, Sarver, Aaron L, Modiano, Jaime F., Weiss, Robert H.
Publicado no Oncotarget (2016)

Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis

Por Zhang, Guodong, Panigrahy, Dipak, Hwang, Sung Hee, Yang, Jun, Mahakian, Lisa M., Wettersten, Hiromi I., Liu, Jun-Yan, Wang, Yanru, Ingham, Elizabeth S., Tam, Sarah, Kieran, Mark W., Weiss, Robert H., Ferrara, Katherine W., Hammock, Bruce D.
Publicado em 2014

Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis

Por Wettersten, Hiromi I., Hakimi, A. Ari, Morin, Dexter, Bianchi, Cristina, Johnstone, Megan E., Donohoe, Dallas R., Trott, Josephine F., Aboud, Omran Abu, Stirdivant, Steven, Neri, Bruce, Wolfert, Robert, Stewart, Benjamin, Perego, Roberto, Hsieh, James J., Weiss, Robert H.
Publicado no Cancer Res (2015)

Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis

Por Zhang, Guodong, Panigrahy, Dipak, Mahakian, Lisa M., Yang, Jun, Liu, Jun-Yan, Stephen Lee, Kin Sing, Wettersten, Hiromi I., Ulu, Arzu, Hu, Xiaowen, Tam, Sarah, Hwang, Sung Hee, Ingham, Elizabeth S., Kieran, Mark W., Weiss, Robert H., Ferrara, Katherine W., Hammock, Bruce D.
Publicado em 2013

Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A

Por Gupta, Romi, Dong, Yuying, Solomon, Peter D., Wettersten, Hiromi I., Cheng, Christopher J., Min, JIn-Na, Henson, Jeremy, Dogra, Shaillay Kumar, Hwang, Sung H., Hammock, Bruce D., Zhu, Lihua J., Reddel, Roger R., Saltzman, W. Mark, Weiss, Robert H., Chang, Sandy, Green, Michael R., Wajapeyee, Narendra
Publicado em 2014