XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies

Treatment options for high grade urothelial cancers are limited and have remained largely unchanged for several decades. Selinexor (KPT-330), a first in class small molecule that inhibits the nuclear export protein XPO1, has shown efficacy as a single agent treatment for numerous different malignanc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Baek, Han Bit, Lombard, Alan P., Libertini, Stephen J., Fernandez-Rubio, Aleida, Vinall, Ruth, Gandour-Edwards, Regina, Nakagawa, Rachel, Vidallo, Kathleen, Nishida, Kristine, Siddiqui, Salma, Wettersten, Hiromi, Landesman, Yosef, Weiss, Robert H., Ghosh, Paramita M., Mudryj, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195388/
https://ncbi.nlm.nih.gov/pubmed/30349650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26179
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados