The p14ARF tumor suppressor restrains androgen receptor activity and prevents apoptosis in prostate cancer cells

Prostate cancer (PCa) is characterized by a unique dependence on optimal androgen receptor (AR) activity where physiological androgen concentrations induce proliferation but castrate and supraphysiological levels suppress growth. This feature has been exploited in bipolar androgen therapy (BAT) for...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Siddiqui, Salma, Libertini, Stephen J., Lucas, Christopher A., Lombard, Alan P., Baek, Han Bit, Nakagawa, Rachel M., Nishida, Kristine S., Steele, Thomas M., Melgoza, Frank U., Borowsky, Alexander D., Durbin-Johnson, Blythe P., Qi, LiHong, Ghosh, Paramita M., Mudryj, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034238/
https://ncbi.nlm.nih.gov/pubmed/32330514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.03.030
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