Depletion of androgen receptor low molecular weight isoform reduces bladder tumor cell viability and induces apoptosis

Bladder cancer (BlCa) exhibits a gender disparity where men are three times more likely to develop the malignancy than women suggesting a role for the androgen receptor (AR). Here we report that BlCa cells express low molecular weight (LMW) AR isoforms that are missing the ligand binding domain (LBD...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Katleba, Kimberley, Lombard, Alan P., Tsamouri, Maria-Malvina, Baek, Han Bit, Nishida, Kristine S., Libertini, Stephen J., Platero, Alexander J., Ma, Ai-Hong, Pan, Chong-xian, Ghosh, Paramita M., Mudryj, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943249/
https://ncbi.nlm.nih.gov/pubmed/33549708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2021.01.029
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