Specific Inhibition of the Nuclear Exporter Exportin-1 Attenuates Kidney Cancer Growth

PURPOSE: Despite the advent of FDA-approved therapeutics to a limited number of available targets (kinases and mTOR), PFS of kidney cancer (RCC) has been extended only one to two years due to the development of drug resistance. Here, we evaluate a novel therapeutic for RCC which targets the exportin...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Wettersten, Hiromi I., Landesman, Yosef, Friedlander, Sharon, Shacham, Sharon, Kauffman, Michael, Weiss, Robert H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252068/
https://ncbi.nlm.nih.gov/pubmed/25461627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113867
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