Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis

Epidemiological and preclinical evidence supports that omega-3 dietary fatty acids (fish oil) reduce the risks of macular degeneration and cancers, but the mechanisms by which these omega-3 lipids inhibit angiogenesis and tumorigenesis are poorly understood. Here we show that epoxydocosapentaenoic a...

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Detalhes bibliográficos
Main Authors: Zhang, Guodong, Panigrahy, Dipak, Mahakian, Lisa M., Yang, Jun, Liu, Jun-Yan, Stephen Lee, Kin Sing, Wettersten, Hiromi I., Ulu, Arzu, Hu, Xiaowen, Tam, Sarah, Hwang, Sung Hee, Ingham, Elizabeth S., Kieran, Mark W., Weiss, Robert H., Ferrara, Katherine W., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631682/
https://ncbi.nlm.nih.gov/pubmed/23553837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304321110
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