Combinatorial Chemistry in Drug Discovery

per Liu, Ruiwu, Li, Xiaocen, Lam, Kit S.
Publicat a Curr Opin Chem Biol (2017)

Development of Hydrogel TentaGel Shell-Core Beads for Ultra-high Throughput Solution Phase Screening of Encoded OBOC Combinatorial Small Molecule Libraries

per Gee Baek, Hyoung, Liu, Ruiwu, Lam, Kit S.
Publicat 2009

Tumor-targeting peptides from combinatorial libraries

per Liu, Ruiwu, Li, Xiaocen, Xiao, Wenwu, Lam, Kit S.
Publicat a Adv Drug Deliv Rev (2016)

Jeffamine Derivatized TentaGel Beads and PDMS Microbead Cassettes for Ultra-high Throughput in situ Releasable Solution-Phase Cell-based Screening of OBOC Combinatorial Small Molec...

per Townsend, Jared B., Shaheen, Farzana, Liu, Ruiwu, Lam, Kit S.
Publicat 2010

Screening of an OBOC combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cells

per Miyamoto, Suzanne, Liu, Ruiwu, Hung, Susan, Wang, Xiaobing, Lam, Kit S.
Publicat 2007

Near-infrared optical imaging in glioblastoma xenograft with ligand targeting α3 integrin

per Xiao, Wenwu, Yao, Nianhuan, Peng, Li, Liu, Ruiwu, Lam, Kit S
Publicat 2008

Alzheimer's Disease Drug Candidates Stabilize A-β Protein Native Structure by Interacting with the Hydrophobic Core

per Li, Jie, Liu, Ruiwu, Lam, Kit S., Jin, Lee-Way, Duan, Yong
Publicat 2011

Small-molecule inhibitors of p21 as novel therapeutics for chemotherapy-resistant kidney cancer

per Liu, Ruiwu, Wettersten, Hiromi I., Park, See-Hyoung, Weiss, Robert H.
Publicat a Future Med Chem (2013)

LAS0811: From Combinatorial Chemistry to Activation of Antioxidant Response Element

per Zhu, Ming, Baek, Hyounggee, Liu, Ruiwu, Song, Aimin, Lam, Kit, Lau, Derick
Publicat 2009

Discovery of Specific Ligands for Oral Squamous Carcinoma to Develop Anti-cancer Drug Loaded Precise Targeting Nanotherapeutics

per Yang, Fan, Liu, Ruiwu, Kramer, Randall, Xiao, WenWu, Jordan, Richard, Lam, Kit S.
Publicat a J Calif Dent Assoc (2012)

Immobilized OBOC combinatorial bead array to facilitate multiplicative screening

per Xiao, Wenwu, Bononi, Fernanda C., Townsend, Jared, Li, Yuanpei, Liu, Ruiwu, Lam, Kit S.
Publicat a Comb Chem High Throughput Screen (2013)

A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation

per Jiang, Min, Liu, Lixian, Liu, Ruiwu, Lam, Kit S., Lane, Nancy E., Yao, Wei
Publicat a BMC Pharmacol Toxicol (2020)

A Novel Galectin-1 Inhibitor Discovered through One-Bead-Two-Compounds Library Potentiates the Anti-tumor Effects of Paclitaxel in vivo

per Shih, Tsung-Chieh, Liu, Ruiwu, Fung, Gabriel, Bhardwaj, Gaurav, Ghosh, Paramita M., Lam, Kit S.
Publicat a Mol Cancer Ther (2017)

An α4β1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice

per Kenyon, Nicholas J., Liu, Ruiwu, O’Roark, Erin M., Huang, Wenzhe, Peng, Li, Lam, Kit S.
Publicat 2008

Design, Synthesis, and Application of OB2C Combinatorial Peptide and Peptidomimetic Libraries

per Liu, Ruiwu, Shih, Tsung-Chieh, Deng, Xiaojun, Anwar, Lara, Ahadi, Sara, Kumaresan, Pappanaicken, Lam, Kit S.
Publicat a Methods Mol Biol (2015)

Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved adhesion, spreading and survival of human chorionic villus-deri...

per Hao, Dake, Ma, Bowen, He, Chuanchao, Liu, Ruiwu, Farmer, Diana L, Lam, Kit S, Wang, Aijun
Publicat a J Mater Chem B (2020)

Synthesis and Characterization of a Novel Inhibitor of C-Reactive Protein–Mediated Proinflammatory Effects

per Kumaresan, Pappanaicken R., Devaraj, Sridevi, Huang, Wenzhe, Lau, Edmond Y., Liu, Ruiwu, Lam, Kit S., Jialal, Ishwarlal
Publicat 2013

Combinatorial Peptide Microarray Synthesis Based on Microfluidic Impact Printing

per Li, Jiannan, Zhao, Siwei, Yang, Gaomai, Liu, Ruiwu, Xiao, Wenwu, Disano, Paolo, Lam, Kit S., Pan, Tingrui
Publicat a ACS Comb Sci (2018)

Extracellular Matrix Mimicking Nanofibrous Scaffolds Modified With Mesenchymal Stem Cell-Derived Extracellular Vesicles for Improved Vascularization

per Hao, Dake, Swindell, Hila Shimshi, Ramasubramanian, Lalithasri, Liu, Ruiwu, Lam, Kit S., Farmer, Diana L., Wang, Aijun
Publicat a Front Bioeng Biotechnol (2020)

Synthesis of two fluorescent GTPγS molecules and their biological relevance

per Trans, Denise J., Bai, Ruoli, Addison, J. Bennet, Liu, Ruiwu, Hamel, Ernest, Coleman, Matthew A., Henderson, Paul T.
Publicat a Nucleosides Nucleotides Nucleic Acids (2017)