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An α4β1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice
Inhibition of the α4 subunit of both the α4β1 and α4β7 integrins has shown promise in decreasing airway inflammation and airway hyperresponsiveness in various animal models. We hypothesized that a novel, high-affinity α4β1 antagonist (LLP2A) would decrease the migration of eosinophils to the lung an...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646171/ https://ncbi.nlm.nih.gov/pubmed/19103195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.11.063 |
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