Jeffamine Derivatized TentaGel Beads and PDMS Microbead Cassettes for Ultra-high Throughput in situ Releasable Solution-Phase Cell-based Screening of OBOC Combinatorial Small Molecule Libraries

A method to efficiently immobilize and partition large quantities of microbeads in an array format in microfabricated polydimethylsiloxane (PDMS) cassette for high-throughput in situ releasable solution-phase cell-based screening of one-bead-one-compound (OBOC) combinatorial libraries is described....

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Hlavní autoři: Townsend, Jared B., Shaheen, Farzana, Liu, Ruiwu, Lam, Kit S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045263/
https://ncbi.nlm.nih.gov/pubmed/20593859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc100083f
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