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Screening of an OBOC combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cells
The search for small molecules that specifically recognize protein targets is a laborious process if conducted in a one protein – one compound manner. A high throughput antibody based screening of "one-bead one-compound" (OBOC) combinatorial small molecule libraries is described here, wher...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770001/ https://ncbi.nlm.nih.gov/pubmed/18023409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.10.028 |
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