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Screening of an OBOC combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cells

The search for small molecules that specifically recognize protein targets is a laborious process if conducted in a one protein – one compound manner. A high throughput antibody based screening of "one-bead one-compound" (OBOC) combinatorial small molecule libraries is described here, wher...

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Hlavní autoři: Miyamoto, Suzanne, Liu, Ruiwu, Hung, Susan, Wang, Xiaobing, Lam, Kit S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770001/
https://ncbi.nlm.nih.gov/pubmed/18023409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.10.028
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