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Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new sight for fetal tissue engineering

Cell-biomaterial interactions are primarily governed by cell adhesion, which arises from the binding of cellular integrins to the extracellular matrix (ECM). Integrins drive the assembly of focal contacts that serve as mechanotransducers and signaling nexuses for stem cells, for example integrin α4β...

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Dettagli Bibliografici
Pubblicato in:J Mater Chem B
Autori principali: Hao, Dake, Ma, Bowen, He, Chuanchao, Liu, Ruiwu, Farmer, Diana L, Lam, Kit S, Wang, Aijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353926/
https://ncbi.nlm.nih.gov/pubmed/32011618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tb02309g
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