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Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new sight for fetal tissue engineering

Cell-biomaterial interactions are primarily governed by cell adhesion, which arises from the binding of cellular integrins to the extracellular matrix (ECM). Integrins drive the assembly of focal contacts that serve as mechanotransducers and signaling nexuses for stem cells, for example integrin α4β...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Mater Chem B
Hauptverfasser: Hao, Dake, Ma, Bowen, He, Chuanchao, Liu, Ruiwu, Farmer, Diana L, Lam, Kit S, Wang, Aijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353926/
https://ncbi.nlm.nih.gov/pubmed/32011618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tb02309g
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