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Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases
Serine hydrolase inhibitors, which facilitate enzyme function assignment and are used to treat a range of human disorders, often act by an irreversible mechanism that involves covalent modification of the serine hydrolase catalytic nucleophile. The portion of mammalian serine hydrolases for which se...
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| Publicado en: | Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527528/ https://ncbi.nlm.nih.gov/pubmed/26120000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.018 |
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