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Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases

Serine hydrolase inhibitors, which facilitate enzyme function assignment and are used to treat a range of human disorders, often act by an irreversible mechanism that involves covalent modification of the serine hydrolase catalytic nucleophile. The portion of mammalian serine hydrolases for which se...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Biol
Egile Nagusiak: Cognetta, Armand B., Niphakis, Micah J., Lee, Hyeon-Cheol, Martini, Michael L., Hulce, Jonathan J., Cravatt, Benjamin F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527528/
https://ncbi.nlm.nih.gov/pubmed/26120000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.018
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