Wird geladen...

O-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

[Image: see text] The two major endocannabinoid transmitters, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are degraded by distinct enzymes in the nervous system, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively. FAAH and MAGL inhibitors cause elevations in b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Niphakis, Micah J., Johnson, Douglas S., Ballard, T. Eric, Stiff, Cory, Cravatt, Benjamin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2011
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382460/
https://ncbi.nlm.nih.gov/pubmed/22860211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200089j
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!