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Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases
Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) are two enzymes from the serine hydrolase superfamily that degrade the endocannabinoids 2-arachidonoylglycerol and anandamide, respectively. We have recently discovered that MAGL and FAAH are both inhibited by carbamates bearing an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828288/ https://ncbi.nlm.nih.gov/pubmed/20099888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9016976 |
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