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Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

One of the molecular hallmarks of amyloidoses is ordered protein aggregation involving the initial formation of soluble protein oligomers that eventually grow into insoluble fibrils. The identification and characterization of molecular species critical for amyloid fibril formation and disease develo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Frangolho, Ana, Correia, Bruno E., Vaz, Daniela C., Almeida, Zaida L., Brito, Rui M. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730986/
https://ncbi.nlm.nih.gov/pubmed/33287192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235698
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