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Amyloidogenic Potential of Transthyretin Variants: INSIGHTS FROM STRUCTURAL AND COMPUTATIONAL ANALYSES
Human transthyretin (TTR) is an amyloidogenic protein whose mild amyloidogenicity is enhanced by many point mutations affecting considerably the amyloid disease phenotype. To ascertain whether the high amyloidogenic potential of TTR variants may be explained on the basis of the conformational change...
Gorde:
Egile Nagusiak: | , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Biochemistry and Molecular Biology
2009
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757985/ https://ncbi.nlm.nih.gov/pubmed/19602727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017657 |
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