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Amyloidogenic Potential of Transthyretin Variants: INSIGHTS FROM STRUCTURAL AND COMPUTATIONAL ANALYSES

Human transthyretin (TTR) is an amyloidogenic protein whose mild amyloidogenicity is enhanced by many point mutations affecting considerably the amyloid disease phenotype. To ascertain whether the high amyloidogenic potential of TTR variants may be explained on the basis of the conformational change...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cendron, Laura, Trovato, Antonio, Seno, Flavio, Folli, Claudia, Alfieri, Beatrice, Zanotti, Giuseppe, Berni, Rodolfo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757985/
https://ncbi.nlm.nih.gov/pubmed/19602727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017657
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