Amyloidogenic Potential of Transthyretin Variants: INSIGHTS FROM STRUCTURAL AND COMPUTATIONAL ANALYSES

Human transthyretin (TTR) is an amyloidogenic protein whose mild amyloidogenicity is enhanced by many point mutations affecting considerably the amyloid disease phenotype. To ascertain whether the high amyloidogenic potential of TTR variants may be explained on the basis of the conformational change...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cendron, Laura, Trovato, Antonio, Seno, Flavio, Folli, Claudia, Alfieri, Beatrice, Zanotti, Giuseppe, Berni, Rodolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757985/
https://ncbi.nlm.nih.gov/pubmed/19602727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017657
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados