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Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage

TTR (transthyretin) amyloidoses are diseases characterized by the aggregation and extracellular deposition of the normally soluble plasma protein TTR. Ex vivo and tissue culture studies suggest that tissue damage precedes TTR fibril deposition, indicating that early events in the amyloidogenic casca...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biosci Rep
Egile Nagusiak: Manral, Pallavi, Reixach, Natàlia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293901/
https://ncbi.nlm.nih.gov/pubmed/25395306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140155
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