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Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

The transthyretin (TTR) amyloidoses are human diseases in which the misfolded TTR protein aggregates in tissues with subsequent visceral, peripheral, and autonomic nerve dysfunction. Recent reports have stressed the importance of oligomeric intermediates as major cytotoxic species in various forms o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Reixach, Natàlia, Deechongkit, Songpon, Jiang, Xin, Kelly, Jeffery W., Buxbaum, Joel N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC365703/
https://ncbi.nlm.nih.gov/pubmed/14981241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400062101
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