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Age-related oxidative modifications of transthyretin modulate its amyloidogenicity
The transthyretin amyloidoses are diseases of protein misfolding characterized by the extracellular deposition of fibrils and other aggregates of the homotetrameric protein transthyretin (TTR) in peripheral nerves, heart and other tissues. Age is the major risk factor for the development of these di...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604100/ https://ncbi.nlm.nih.gov/pubmed/23414091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301313b |
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