Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?

Por Buxbaum, Joel N.
Publicado em 2009

Evaluation of tafamidis as first-line therapeutic agent for transthyretin familial amyloidotic polyneuropathy

Por Buxbaum, Joel N
Publicado no Degener Neurol Neuromuscul Dis (2012)

Is Older Colder or Colder Older? The Association of Age With Body Temperature in 18,630 Individuals

Por Waalen, Jill, Buxbaum, Joel N.
Publicado em 2011

Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?

Por Li, Xinyi, Buxbaum, Joel N
Publicado em 2011

Transthyretin: the servant of many masters

Por Buxbaum, Joel N., Reixach, Natàlia
Publicado no Cell Mol Life Sci (2009)

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System

Por Buxbaum, Joel N., Johansson, Jan
Publicado no Front Neurosci (2017)

Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly...

Por Buxbaum, Joel N., Ruberg, Frederick L.
Publicado no Genet Med (2017)

Summary: FASEB Science Research Conference on Protein Aggregation in Health and Disease: June 11-16, 2017, Steamboat Springs, Colorado, USA

Por Buxbaum, Joel N., Morgan, Gareth J.
Publicado no FASEB J (2018)

Age-related oxidative modifications of transthyretin modulate its amyloidogenicity

Por Zhao, Lei, Buxbaum, Joel N, Reixach, Natàlia
Publicado em 2013

The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis

Por Jiang, Xin, Buxbaum, Joel N., Kelly, Jeffery W.
Publicado em 2001

Neuronal Production of Transthyretin in Human and Murine Alzheimer's Disease: Is It Protective?

Por Li, Xinyi, Masliah, Eliezer, Reixach, Natàlia, Buxbaum, Joel N.
Publicado em 2011

Transthyretin Suppresses Amyloid-β secretion by Interfering with Processing of The Amyloid-β Precursor Protein

Por Li, Xinyi, Song, Yuanli, Sanders, Charles R., Buxbaum, Joel N.
Publicado no J Alzheimers Dis (2016)

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

Por Reixach, Natàlia, Deechongkit, Songpon, Jiang, Xin, Kelly, Jeffery W., Buxbaum, Joel N.
Publicado em 2004

The Systemic Amyloid Precursor Transthyretin (TTR) Behaves as a Neuronal Stress Protein Regulated by HSF1 in SH-SY5Y Human Neuroblastoma Cells and APP23 Alzheimer's Disease Model M...

Por Wang, Xin, Cattaneo, Francesca, Ryno, Lisa, Hulleman, John, Reixach, Natàlia, Buxbaum, Joel N.
Publicado em 2014

Inhibition of amyloid beta fibril formation by monomeric human transthyretin

Por Garai, Kanchan, Posey, Ammon E., Li, Xinyi, Buxbaum, Joel N., Pappu, Rohit V.
Publicado no Protein Sci (2018)

Identification of transthyretin as a novel interacting partner for the δ subunit of GABA(A) receptors

Por Zhou, Li, Tang, Xin, Li, Xinyi, Bai, Yuting, Buxbaum, Joel N., Chen, Gong
Publicado no PLoS One (2019)

Mechanisms of Transthyretin Cardiomyocyte Toxicity Inhibition by Resveratrol Analogs

Por Bourgault, Steve, Choi, Sungwook, Buxbaum, Joel N., Kelly, Jeffery W., Price, Joshua L., Reixach, Natàlia
Publicado em 2011

Why are some amyloidoses systemic? Does hepatic “chaperoning at a distance” prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?...

Por Buxbaum, Joel N., Tagoe, Clement, Gallo, Gloria, Walker, John R., Kurian, Sunil, Salomon, Daniel R.
Publicado em 2012

Transthyretin deposition promotes progression of osteoarthritis

Por Matsuzaki, Tokio, Akasaki, Yukio, Olmer, Merissa, Alvarez‐Garcia, Oscar, Reixach, Natalia, Buxbaum, Joel N., Lotz, Martin K.
Publicado no Aging Cell (2017)

Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis

Por Akasaki, Yukio, Reixach, Natàlia, Matsuzaki, Tokio, Alvarez-Garcia, Oscar, Olmer, Merissa, Iwamoto, Yukihide, Buxbaum, Joel N., Lotz, Martin K.
Publicado no Arthritis Rheumatol (2015)