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Transthyretin deposition promotes progression of osteoarthritis

Deposition of amyloid is a common aging‐associated phenomenon in several aging‐related diseases. Osteoarthritis (OA) is the most prevalent joint disease, and aging is its major risk factor. Transthyretin (TTR) is an amyloidogenic protein that is deposited in aging and OA‐affected human cartilage and...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Matsuzaki, Tokio, Akasaki, Yukio, Olmer, Merissa, Alvarez‐Garcia, Oscar, Reixach, Natalia, Buxbaum, Joel N., Lotz, Martin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676063/
https://ncbi.nlm.nih.gov/pubmed/28941045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12665
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