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Transthyretin deposition promotes progression of osteoarthritis

Deposition of amyloid is a common aging‐associated phenomenon in several aging‐related diseases. Osteoarthritis (OA) is the most prevalent joint disease, and aging is its major risk factor. Transthyretin (TTR) is an amyloidogenic protein that is deposited in aging and OA‐affected human cartilage and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Matsuzaki, Tokio, Akasaki, Yukio, Olmer, Merissa, Alvarez‐Garcia, Oscar, Reixach, Natalia, Buxbaum, Joel N., Lotz, Martin K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676063/
https://ncbi.nlm.nih.gov/pubmed/28941045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12665
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