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Transthyretin deposition promotes progression of osteoarthritis

Deposition of amyloid is a common aging‐associated phenomenon in several aging‐related diseases. Osteoarthritis (OA) is the most prevalent joint disease, and aging is its major risk factor. Transthyretin (TTR) is an amyloidogenic protein that is deposited in aging and OA‐affected human cartilage and...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Matsuzaki, Tokio, Akasaki, Yukio, Olmer, Merissa, Alvarez‐Garcia, Oscar, Reixach, Natalia, Buxbaum, Joel N., Lotz, Martin K.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676063/
https://ncbi.nlm.nih.gov/pubmed/28941045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12665
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