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Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration

Aging is a main risk factor for intervertebral disc (IVD) degeneration, the main cause of low back pain. FOXO transcription factors are important regulators of tissue homeostasis and longevity. Here, we determined the expression pattern of FOXO in healthy and degenerated human IVD and the associatio...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Alvarez-Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Masuda, Koichi, Lotz, Martin K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650945/
https://ncbi.nlm.nih.gov/pubmed/28430387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23583
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