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FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration

Intervertebral disk (IVD) degeneration is a prevalent age‐associated musculoskeletal disorder and a major cause of chronic low back pain. Aging is the main risk factor for the disease, but the molecular mechanisms regulating IVD homeostasis during aging are unknown. The aim of this study was to inve...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Aging Cell
मुख्य लेखकों: Alvarez‐Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Miyata, Kohei, Mokuda, Sho, Sakai, Daisuke, Masuda, Koichi, Asahara, Hiroshi, Lotz, Martin K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156454/
https://ncbi.nlm.nih.gov/pubmed/29963746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12800
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