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FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration
Intervertebral disk (IVD) degeneration is a prevalent age‐associated musculoskeletal disorder and a major cause of chronic low back pain. Aging is the main risk factor for the disease, but the molecular mechanisms regulating IVD homeostasis during aging are unknown. The aim of this study was to inve...
Gespeichert in:
| Veröffentlicht in: | Aging Cell |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156454/ https://ncbi.nlm.nih.gov/pubmed/29963746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12800 |
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