Wwp2 maintains cartilage homeostasis through regulation of Adamts5

The WW domain-containing protein 2 (Wwp2) gene, the host gene of miR-140, codes for the Wwp2 protein, which is an HECT-type E3 ubiquitin ligases abundantly expressed in articular cartilage. However, its function remains unclear. Here, we show that mice lacking Wwp2 and mice in which the Wwp2 E3 enzy...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Mokuda, Sho, Nakamichi, Ryo, Matsuzaki, Tokio, Ito, Yoshiaki, Sato, Tempei, Miyata, Kohei, Inui, Masafumi, Olmer, Merissa, Sugiyama, Eiji, Lotz, Martin, Asahara, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546747/
https://ncbi.nlm.nih.gov/pubmed/31160553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10177-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker