Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage

TTR (transthyretin) amyloidoses are diseases characterized by the aggregation and extracellular deposition of the normally soluble plasma protein TTR. Ex vivo and tissue culture studies suggest that tissue damage precedes TTR fibril deposition, indicating that early events in the amyloidogenic casca...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Manral, Pallavi, Reixach, Natàlia
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2015
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293901/
https://ncbi.nlm.nih.gov/pubmed/25395306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140155
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