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Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites

Transthyretin (TTR) is an amyloidogenic protein, the amyloidogenic potential of which is enhanced by a number of specific point mutations. The ability to inhibit TTR fibrillogenesis is known for several classes of compounds, including natural polyphenols, which protect the native state of TTR by spe...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Florio, Paola, Folli, Claudia, Cianci, Michele, Del Rio, Daniele, Zanotti, Giuseppe, Berni, Rodolfo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705982/
https://ncbi.nlm.nih.gov/pubmed/26468275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.690172
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