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The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans
BACKGROUND: Approximately 4% of black Americans carry a valine-to-isoleucine substitution (V122I) in the transthyretin protein, which has been associated with late-onset restrictive amyloid cardiomyopathy and increased risks of death and heart failure. METHODS: We determined genotype status for the...
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| Publicado no: | N Engl J Med |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382209/ https://ncbi.nlm.nih.gov/pubmed/25551524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1404852 |
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