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2G12-Expressing B Cell Lines May Aid in HIV Carbohydrate Vaccine Design Strategies
The highly conserved cluster of high-mannose glycans on the HIV-1 envelope glycoprotein, gp120, has been highlighted as a target for neutralizing antibodies. 2G12, the first HIV-1 antiglycan neutralizing antibody described, binds with an unusual domain-exchanged structure that creates a high-affinit...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3571453/ https://ncbi.nlm.nih.gov/pubmed/23221565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02820-12 |
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