2G12-Expressing B Cell Lines May Aid in HIV Carbohydrate Vaccine Design Strategies

The highly conserved cluster of high-mannose glycans on the HIV-1 envelope glycoprotein, gp120, has been highlighted as a target for neutralizing antibodies. 2G12, the first HIV-1 antiglycan neutralizing antibody described, binds with an unusual domain-exchanged structure that creates a high-affinit...

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Detaylı Bibliyografya
Asıl Yazarlar: Doores, Katie J., Huber, Michael, Le, Khoa M., Wang, Sheng-Kai, Doyle-Cooper, Colleen, Cooper, Anthony, Pantophlet, Ralph, Wong, Chi-Huey, Nemazee, David, Burton, Dennis R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571453/
https://ncbi.nlm.nih.gov/pubmed/23221565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02820-12
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