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Comparing Antigenicity and Immunogenicity of Engineered gp120

We have engineered monomeric gp120 in such a way as to favorably present the conserved epitope for the broadly neutralizing antibody b12 while lowering the exposure of epitopes recognized by some weakly neutralizing and nonneutralizing antibodies. The work presented here describes the immune respons...

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Main Authors: Selvarajah, Suganya, Puffer, Bridget, Pantophlet, Ralph, Law, Mansun, Doms, Robert W., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211546/
https://ncbi.nlm.nih.gov/pubmed/16160142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12148-12163.2005
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