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Comparing Antigenicity and Immunogenicity of Engineered gp120

We have engineered monomeric gp120 in such a way as to favorably present the conserved epitope for the broadly neutralizing antibody b12 while lowering the exposure of epitopes recognized by some weakly neutralizing and nonneutralizing antibodies. The work presented here describes the immune respons...

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Main Authors: Selvarajah, Suganya, Puffer, Bridget, Pantophlet, Ralph, Law, Mansun, Doms, Robert W., Burton, Dennis R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211546/
https://ncbi.nlm.nih.gov/pubmed/16160142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12148-12163.2005
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