Comparing Antigenicity and Immunogenicity of Engineered gp120

We have engineered monomeric gp120 in such a way as to favorably present the conserved epitope for the broadly neutralizing antibody b12 while lowering the exposure of epitopes recognized by some weakly neutralizing and nonneutralizing antibodies. The work presented here describes the immune respons...

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Hlavní autoři: Selvarajah, Suganya, Puffer, Bridget, Pantophlet, Ralph, Law, Mansun, Doms, Robert W., Burton, Dennis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211546/
https://ncbi.nlm.nih.gov/pubmed/16160142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12148-12163.2005
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