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Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design

The ability to induce broadly neutralizing antibodies should be a key component of any forthcoming vaccine against human immunodeficiency virus type 1. One potential vaccine candidate, monomeric gp120, has generally failed to elicit such antibodies. We postulated that gp120 might be a better immunog...

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Autores principales: Pantophlet, Ralph, Wilson, Ian A., Burton, Dennis R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC154011/
https://ncbi.nlm.nih.gov/pubmed/12719582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5889-5901.2003
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