Molecular Features of the Broadly Neutralizing Immunoglobulin G1 b12 Required for Recognition of Human Immunodeficiency Virus Type 1 gp120

IgG1 b12 is a broadly neutralizing antibody against human immunodeficiency virus type 1 (HIV-1). The epitope recognized by b12 overlaps the CD4 receptor-binding site (CD4bs) on gp120 and has been a target for vaccine design. Determination of the three-dimensional structure of immunoglobulin G1 (IgG1...

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Publicado no:	J Virol
Principais autores:	Zwick, Michael B., Parren, Paul W. H. I., Saphire, Erica O., Church, Sarah, Wang, Meng, Scott, Jamie K., Dawson, Philip E., Wilson, Ian A., Burton, Dennis R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12719580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.10.5863-5876.2003
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