Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design

The ability to induce broadly neutralizing antibodies should be a key component of any forthcoming vaccine against human immunodeficiency virus type 1. One potential vaccine candidate, monomeric gp120, has generally failed to elicit such antibodies. We postulated that gp120 might be a better immunog...

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Hlavní autoři: Pantophlet, Ralph, Wilson, Ian A., Burton, Dennis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC154011/
https://ncbi.nlm.nih.gov/pubmed/12719582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5889-5901.2003
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