Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo

Humanized mice reconstituted with a human immune system can be mucosally infected with human immunodeficiency virus (HIV), opening up the possibility of studying HIV transmission in a small-animal model. Here we report that passive immunization with the broadly neutralizing antibody b12 protected hu...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Deruaz, Maud, Moldt, Brian, Le, Khoa M., Power, Karen A., Vrbanac, Vladimir D., Tanno, Serah, Ghebremichael, Musie S., Allen, Todd M., Tager, Andrew M., Burton, Dennis R., Luster, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957443/
https://ncbi.nlm.nih.gov/pubmed/27357340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw203
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