What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans?: Rigorous Simian Immunodeficiency Virus Vaccine Trials Can Be Instructive

מאת Martins, Mauricio A., Watkins, David I.
הוצא לאור ב Cold Spring Harb Perspect Biol (2018)

Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8(+) T Cell Killing

מאת Rainho, Jennifer N., Martins, Mauricio A., Cunyat, Francesc, Watkins, Ian T., Watkins, David I., Stevenson, Mario
הוצא לאור ב J Virol (2015)

T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge

מאת Martins, Mauricio A., Wilson, Nancy A., Reed, Jason S., Ahn, Chanook D., Klimentidis, Yann C., Allison, David B., Watkins, David I.
יצא לאור 2010

Analysis of Simian Immunodeficiency Virus-specific CD8(+) T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining

מאת Gonzalez-Nieto, Lucas, Domingues, Aline, Ricciardi, Michael, Gutman, Martin J., Maxwell, Helen S., Pedreño-Lopez, Nuria, Bailey, Varian, Magnani, Diogo M., Martins, Mauricio A.
הוצא לאור ב J Vis Exp (2016)

Recombinant Herpesvirus Vectors: Durable Immune Responses and Durable Protection against Simian Immunodeficiency Virus SIVmac239 Acquisition

מאת Castro, Isabelle M., Ricciardi, Michael J., Gonzalez-Nieto, Lucas, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I., Martins, Mauricio A.
הוצא לאור ב J Virol (2021)

A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products

מאת Shin, Young C., Bischof, Georg F., Lauer, William A., Gonzalez-Nieto, Lucas, Rakasz, Eva G., Hendricks, Gregory M., Watkins, David I., Martins, Mauricio A., Desrosiers, Ronald C.
הוצא לאור ב PLoS Pathog (2018)

Vaccine protection against SIVmac239 acquisition

מאת Martins, Mauricio A., Bischof, Georg F., Shin, Young C., Lauer, William A., Gonzalez-Nieto, Lucas, Watkins, David I., Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C.
הוצא לאור ב Proc Natl Acad Sci U S A (2019)

The Majority of Freshly Sorted Simian Immunodeficiency Virus (SIV)-Specific CD8(+) T Cells Cannot Suppress Viral Replication in SIV-Infected Macrophages

מאת Vojnov, Lara, Martins, Mauricio A., Bean, Alexander T., Veloso de Santana, Marlon G., Sacha, Jonah B., Wilson, Nancy A., Bonaldo, Myrna C., Galler, Ricardo, Stevenson, Mario, Watkins, David I.
יצא לאור 2012

A Recombinant Rhesus Monkey Rhadinovirus Deleted of Glycoprotein L Establishes Persistent Infection of Rhesus Macaques and Elicits Conventional T Cell Responses

מאת Hahn, Alexander S., Bischof, Georg F., Großkopf, Anna K., Shin, Young C., Domingues, Aline, Gonzalez-Nieto, Lucas, Rakasz, Eva G., Watkins, David I., Ensser, Armin, Martins, Mauricio A., Desrosiers, Ronald C.
הוצא לאור ב J Virol (2020)

CD8(+) gamma-delta TCR(+) and CD4(+) T cells produce IFN-γat 5–7 days after yellow fever vaccination in Indian rhesus macaques, before the induction of classical antigen-specific T...

מאת Neves, Patrícia C. C., Rudersdorf, Richard A., Galler, Ricardo, Bonaldo, Myrna C., de Santana, Marlon Gilsepp Veloso, Mudd, Philip A., Martins, Maurício A., Rakasz, Eva G., Wilson, Nancy A., Watkins, David I.
יצא לאור 2010

Gag- and Nef-specific CD4(+) T cells recognize and inhibit SIV replication in infected macrophages early after infection

מאת Sacha, Jonah B., Giraldo-Vela, Juan P., Buechler, Matthew B., Martins, Mauricio A., Maness, Nicholas J., Chung, Chungwon, Wallace, Lyle T., León, Enrique J., Friedrich, Thomas C., Wilson, Nancy A., Hiraoka, Atsunobu, Watkins, David I.
יצא לאור 2009

Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates.*

מאת Hangartner, Lars, Beauparlant, David, Rakasz, Eva, Nedellec, Rebecca, Hozé, Nathanaël, McKenney, Katherine, Martins, Mauricio A., Seabright, Gemma E., Allen, Joel D., Weiler, Andrea M., Friedrich, Thomas C., Regoes, Roland R., Crispin, Max, Burton, Dennis R.
הוצא לאור ב Sci Transl Med (2021)

Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques

מאת Pedreño-Lopez, Nuria, Rosen, Brandon C., Flores, Walter J., Gorman, Matthew J., Voigt, Thomas B., Ricciardi, Michael J., Crosno, Kristin, Weisgrau, Kim L., Parks, Christopher L., Lifson, Jeffrey D., Alter, Galit, Rakasz, Eva G., Magnani, Diogo M., Martins, Mauricio A., Watkins, David I.
הוצא לאור ב Front Immunol (2021)

Recombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8(+) T-Cell Responses in Rhesus Macaques

מאת Bonaldo, Myrna C., Martins, Mauricio A., Rudersdorf, Richard, Mudd, Philip A., Sacha, Jonah B., Piaskowski, Shari M., Costa Neves, Patrícia C., Veloso de Santana, Marlon G., Vojnov, Lara, Capuano, Saverio, Rakasz, Eva G., Wilson, Nancy A., Fulkerson, John, Sadoff, Jerald C., Watkins, David I., Galler, Ricardo
יצא לאור 2010

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

מאת Martins, Mauricio A., Gonzalez-Nieto, Lucas, Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Bischof, Georg F., Pedreño-Lopez, Nuria, Pauthner, Matthias G., Burton, Dennis R., Parks, Christopher L., Earl, Patricia, Moss, Bernard, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
הוצא לאור ב J Virol (2020)

Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques

מאת Gonzalez-Nieto, Lucas, Castro, Isabelle M., Bischof, Georg F., Shin, Young C., Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Pedreño-Lopez, Nuria, Magnani, Diogo M., Ejima, Keisuke, Allison, David B., Gil, Hwi Min, Evans, David T., Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Martins, Mauricio A.
הוצא לאור ב PLoS Pathog (2019)

Immunogenicity of Seven New Recombinant Yellow Fever Viruses 17D Expressing Fragments of SIVmac239 Gag, Nef, and Vif in Indian Rhesus Macaques

מאת Martins, Mauricio A., Bonaldo, Myrna C., Rudersdorf, Richard A., Piaskowski, Shari M., Rakasz, Eva G., Weisgrau, Kim L., Furlott, Jessica R., Eernisse, Christopher M., Veloso de Santana, Marlon G., Hidalgo, Bertha, Friedrich, Thomas C., Chiuchiolo, Maria J., Parks, Christopher L., Wilson, Nancy A., Allison, David B., Galler, Ricardo, Watkins, David I.
יצא לאור 2013

Vaccination with gag, vif, and nef Gene Fragments Affords Partial Control of Viral Replication after Mucosal Challenge with SIVmac239

מאת Martins, Mauricio A., Wilson, Nancy A., Piaskowski, Shari M., Weisgrau, Kim L., Furlott, Jessica R., Bonaldo, Myrna C., Veloso de Santana, Marlon G., Rudersdorf, Richard A., Rakasz, Eva G., Keating, Karen D., Chiuchiolo, Maria J., Piatak, Michael, Allison, David B., Parks, Christopher L., Galler, Ricardo, Lifson, Jeffrey D., Watkins, David I.
יצא לאור 2014

The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08(+) Rhesus Macaques

מאת Martins, Mauricio A., Gonzalez-Nieto, Lucas, Shin, Young C., Domingues, Aline, Gutman, Martin J., Maxwell, Helen S., Magnani, Diogo M., Ricciardi, Michael J., Pedreño-Lopez, Núria, Bailey, Varian K., Altman, John D., Parks, Christopher L., Allison, David B., Ejima, Keisuke, Rakasz, Eva G., Capuano, Saverio, Desrosiers, Ronald C., Lifson, Jeffrey D., Watkins, David I.
הוצא לאור ב J Virol (2019)

Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8(+) T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection

מאת Martins, Mauricio A., Tully, Damien C., Cruz, Michael A., Power, Karen A., Veloso de Santana, Marlon G., Bean, David J., Ogilvie, Colin B., Gadgil, Rujuta, Lima, Noemia S., Magnani, Diogo M., Ejima, Keisuke, Allison, David B., Piatak, Michael, Altman, John D., Parks, Christopher L., Rakasz, Eva G., Capuano, Saverio, Galler, Ricardo, Bonaldo, Myrna C., Lifson, Jeffrey D., Allen, Todd M., Watkins, David I.
הוצא לאור ב J Virol (2015)