Recombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8(+) T-Cell Responses in Rhesus Macaques

Here we describe a novel vaccine vector for expressing human immunodeficiency virus (HIV) antigens. We show that recombinant attenuated yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 Gag sequences can be used as a vector to generate SIV-specific CD8(+) T-cell respo...

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Auteurs principaux: Bonaldo, Myrna C., Martins, Mauricio A., Rudersdorf, Richard, Mudd, Philip A., Sacha, Jonah B., Piaskowski, Shari M., Costa Neves, Patrícia C., Veloso de Santana, Marlon G., Vojnov, Lara, Capuano, Saverio, Rakasz, Eva G., Wilson, Nancy A., Fulkerson, John, Sadoff, Jerald C., Watkins, David I., Galler, Ricardo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838090/
https://ncbi.nlm.nih.gov/pubmed/20089645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02255-09
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