Recombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8(+) T-Cell Responses in Rhesus Macaques

Here we describe a novel vaccine vector for expressing human immunodeficiency virus (HIV) antigens. We show that recombinant attenuated yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 Gag sequences can be used as a vector to generate SIV-specific CD8(+) T-cell respo...

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Detalhes bibliográficos
Main Authors: Bonaldo, Myrna C., Martins, Mauricio A., Rudersdorf, Richard, Mudd, Philip A., Sacha, Jonah B., Piaskowski, Shari M., Costa Neves, Patrícia C., Veloso de Santana, Marlon G., Vojnov, Lara, Capuano, Saverio, Rakasz, Eva G., Wilson, Nancy A., Fulkerson, John, Sadoff, Jerald C., Watkins, David I., Galler, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838090/
https://ncbi.nlm.nih.gov/pubmed/20089645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02255-09
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