A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products

The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus monkey rhadinovirus (RRV), a gamma-2 herpesvir...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Shin, Young C., Bischof, Georg F., Lauer, William A., Gonzalez-Nieto, Lucas, Rakasz, Eva G., Hendricks, Gregory M., Watkins, David I., Martins, Mauricio A., Desrosiers, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023237/
https://ncbi.nlm.nih.gov/pubmed/29912986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007143
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