Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

BG505 SOSIP is a well-characterized near-native recombinant HIV Envelope (Env) trimer that holds promise as part of a sequential HIV immunogen regimen to induce broadly neutralizing antibodies (bnAbs). Rhesus macaques are considered the most appropriate pre-clinical animal model for monitoring antib...

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Udgivet i:Cell Rep
Main Authors: Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487785/
https://ncbi.nlm.nih.gov/pubmed/32905766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108122
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