Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

The development of stabilized recombinant HIV envelope trimers that mimic the virion surface molecule has increased enthusiasm for a neutralizing antibody (nAb)-based HIV vaccine. However, there is limited experience with recombinant trimers as immunogens in nonhuman primates, which are typically us...

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Bibliografski detalji
Izdano u:Immunity
Glavni autori: Pauthner, Matthias, Havenar-Daughton, Colin, Sok, Devin, Nkolola, Joseph P., Bastidas, Raiza, Boopathy, Archana V., Carnathan, Diane G., Chandrashekar, Abishek, Cirelli, Kimberly M., Cottrell, Christopher A., Eroshkin, Alexey M., Guenaga, Javier, Kaushik, Kirti, Kulp, Daniel W., Liu, Jinyan, McCoy, Laura E., Oom, Aaron L., Ozorowski, Gabriel, Post, Kai W., Sharma, Shailendra K., Steichen, Jon M., de Taeye, Steven W., Tokatlian, Talar, Torrents de la Peña, Alba, Butera, Salvatore T., LaBranche, Celia C., Montefiori, David C., Silvestri, Guido, Wilson, Ian A., Irvine, Darrell J., Sanders, Rogier W., Schief, William R., Ward, Andrew B., Wyatt, Richard T., Barouch, Dan H., Crotty, Shane, Burton, Dennis R.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483234/
https://ncbi.nlm.nih.gov/pubmed/28636956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.05.007
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